Diabetic Nephropathy Zebrafish

Perlecan - Wikipedia, The Free Encyclopedia
Perlecan knockdown in embryonic zebrafish has been achieved through the use of Morpholinos Decreased perlecan in the glomerular basement membrane has a central role in the development of diabetic albuminuria. Perlecan expression is down regulated by many atherogenic stimuli and thus Perlecan ... Read Article

Notch Signaling, Wt1 And Foxc2 Are Key Regulators Of The ...
Studies in zebrafish and Xenopus show that Wt1 is also important for glomerulogenesis in the pronephros (Majumdar et al., 2000; Taelman et al., 2006; Perner et al., 2007). Other podocyte transcription factors develop weaker podocyte ... Fetch Content

Physiology
24 hypertension, diabetic nephropathy and cardiomyopathy, glomerulosclerosis, and 25 choroidal neovascularization. 26 27 Although the PRR was only identified as a receptor for renin and prorenin 14 28 31 zebrafish(1) is lethal. Moreover, ... Return Doc

Prorenin Specific Of Angiotensin II-mediated Effects In ...
Prorenin specific of angiotensin II-mediated effects in tissue damage: Chair - Duncan Campbell zebrafish using morpholino-antisense oligonucleotides progression of diabetic nephropathy ... Doc Viewer

JoVE Clinical And Translational Medicine - Researchgate.net
JoVE Clinical and Translational Medicine Date Published: 2/28/2013, Issue 72; doi: associated with diabetic retinopathy, diabetic nephropathy and impaired wound diabetic zebrafish not only display the known human secondary complications but ... Fetch Content

Past Basic Science Conferences (2003-2012) - Med.umich.edu
Past Basic Science Conferences (2003-2012) Date TitlePresenter 5/15/2012 Zebrafish: A New Model System for Renal Glomerular Research W. Zhou (UM Peds) 2/7/2012 Diabetic Nephropathy: From Mouse to Human and Back Again Brosius ... View This Document

KIM-1 Driving Chronic Kidney Disease - Nature
KIM-1 driving chronic kidney disease By Benjamin Boettner, Assistant Editor studies in mouse and zebrafish models of diabetic nephropathy kidney disease. The findings are available for licensing, and KIM-1 patents have been ... Document Viewer

A Remote Cis-Acting Variant At 3q Links Glomerular NCK1 To ...
A Remote Cis-Acting Variant at 3q Links Glomerular NCK1 to Diabetic Nephropathy Bing He, Anne-May O¨ sterholm, Juha R. M. Ojala, Ann-Charlotte Andersson, Karl Tryggvason* ... Access Doc

JOURNAL OF In Vivo ENDOCRINOLOGY
JOURNAL OF ENDOCRINOLOGY PHYSIOLOGY, METABOLISM AND TRANSLATION Autophagy in diabetic nephropathy R15–R30 results in heart failure and a diabetic phenotype in zebrafish 1–15 Vanesa Jiménez-Amilburu, Susanne Jong-Raadsen, ... Document Viewer

Division Of Nephrology - Beth Israel Deaconess Medical Center
Division of Nephrology • Overview genesis, diabetic nephropathy and fibrosis. Ion and water transport – The labo-ratories of Drs. Alper, Zeidel, Zebrafish are being used to discover novel genes critical in vessel development. ... Get Doc

Genetic And Biological Effects Of Sodium-Chloride ...
Genetic and Biological Effects of Sodium-Chloride Cotransporter ( SLC12A3) in Diabetic Nephropathy of zebrafish ortholog, slc12a3 led to structural abnormality of kidney pronephric distal duct at 1-cell stage. Slc12a3 mRNA ... Fetch Here

The Presystemic Interplay Between Gut Microbiota And Orally ...
Tyrosine kinase inhibitor II-induced blood vessel loss model in zebrafish. More interestingly, the incubation of C7G with gut microbiota from both normal and colitic and diabetic nephropathy (WO2010/081264 A1). However, ... View Document

Medaka Workshop Report - National Institutes Of Health
Workshop Report . 2 . 3 Table of Contents A The Medaka Model and Human Disease 7 Session 2: Comparative Medaka and Zebrafish Models 8 Session 3: Recommendations on Mechanisms to fibrosis, hypohidrotic ectodermal dysplasia, diabetic nephropathy, and chronic mycobacterial ... Fetch Full Source

CURRICULUM VITAE - NCCIH
CURRICULUM VITAE Josephine P. Briggs, M.D. Business Address: Health Trans-NIH Zebrafish Coordinating Committee. 25. Meyers CM, Briggs JP. Silymarin for diabetic nephropathy: the challenges of botanical product research. Am J Kidney Dis 2012 Dec;60(6):887-889. ... Read Here

A zebrafish Model Of Conditional Targeted Podocyte Ablation ...
A zebrafish model of conditional targeted podocyte ablation and regeneration (Article begins on next page) diabetic nephropathy and HIV nephropathy (1, 2, 3, 4–6). Podocyte depletion leads to glomerulosclerosis in murine models and recent ... Retrieve Here

MOLECULAR AND EMBRYOLOGIC ANALYSES OF THE ER STRESS REGULATOR ...
IN ZEBRAFISH EMBRYOS A Major Qualifying Project Report Submitted to the Faculty of the These patients develop diabetic complications, which involves loss of normal tissue function. Cell death via the endoplasmic reticulum (ER) stress pathway in ... Retrieve Full Source

Nerve Conduction Study - Wikipedia, The Free Encyclopedia
A nerve conduction study (NCS) is a medical diagnostic test commonly used to evaluate the function, especially the ability of electrical conduction, of the motor and sensory nerves of the human body. ... Read Article

Video abstract of review paper “Diabetes reversal via gene transfer: building on successes in animal models” published in the open access journal Research and Reports in Endocrine Disorders by Gerace D, Martiniello-Wilks R, Simpson AM. ... View Video

Induction Of Hyperglycaemia In zebrafish (<Emphasis Type ...
Nephropathy. Animal models have been developed to examine the immunological aspects of type 1 diabetes and the pathogenic mechanisms associated with diabetic retinopathy, but the methods of diabetes induction raise zebrafish to either a 2% or 0% glucose solution, alternat- ... Read Document

16.38 CHARACTERIZATION OF NOVEL GLOMERULAR PROTEINS ROLE IN ...
CHARACTERIZATION OF NOVEL GLOMERULAR PROTEINS: ROLE IN PHYSIOLOGY AND DISEASE Ann-Charlotte Andersson zebrafish larvae it was demonstrated that TDRD5 expression is required for the The diabetic nephropathy associated single nucleotide polymorphism 3q locus was ... Document Viewer

The Biology Of The (Pro)Renin Receptor - Jasn.asnjournals.org
Diabetic nephropathy and cardiac fibro-sis, and that tissue damage could be to-tally prevented by blocking prorenin bindingtoPRR.Herewesummarizeour Zebrafish embryo mutants for V-ATPase subunits, and for PRR/ATP6ap2, display similar pheno- ... Fetch Content

VOLUME 224 ENDOCRINOLOGY
VOLUME 224 ISSN 0022--0795 (PRINT) ISSN 1479--6805 (ONLINE transgenic animals Morag J Young & Amanda J Rickard R1--R13 Autophagy in diabetic nephropathy Yan Ding & Mary E Choi R15--R30 Genetics of primary and a diabetic phenotype in zebrafish Vanesa Jime´nez-Amilburu, Susanne ... Content Retrieval